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IMT Harmony Cryo

Highly configurable directional freezing
yielding reduced cell damage and fast
optimisation of protocols

Multithermal gradient (MTG) directional freezing system

Harmony Cryo is a multithermal gradient (MTG) directional freezing system that offers complete control over key parameters in the cryo preservation process, resulting in fast protocol optimisation and potential increases in post-thaw survival and viability.

MTG directional freezing technology makes it possible to reduce the cellular damage associated with LN2 vapour freezing methods, improving results and allowing for cryo preservation of sperm which may otherwise be ‘unfreezable’. Not only that, but it also enables freezing in large volumes (up to 8ml).

The configurability of the device itself allows for fast protocol optimisation to maximise cell survival. This enables larger scale deployment, saves time and limits wastage of scarce resources, improving efficiency and cost of research projects.

J. K. O’Brien & T. R. Robeck, SeaWorld and Busch Gardens Reproductive Research Centre, USA

Directional freezing resulted in enhanced in vitro quality of spermatozoa derived from liquid-stored semen

Freeze sperm that is otherwise ‘unfreezable’

Our exclusive technology is proven to facilitate higher post-thaw sperm survival compared to LN2 vapour freezing.

It is especially effective in ejaculates where samples are of low sperm quality; semen has been subject to stress, such as sexed semen; and/or where volumes are too large for conventional alternatives.

Quickly hone protocols to optimise sperm survival

Harmony Cryo is highly configurable, facilitating successful cryopreservation at varying volumes, from a range of different species and breeds. The device even allows optimised protocols for individual animals to be saved using the software interface.

The best freezing curve for optimal post-thaw survival can be worked out quickly and repeated consistently.

Harmony Cryo product packages

Harmony Cryo has a number of different product packages depending on the intended use which are bespoke combinations of:

  • Equipment (licensing)
  • Consumables
  • Service and Support
  • Consultancy

Unlock potential

  • Research and conservation – Harmony Cryo is proven worldwide with many endangered species and rare breed work, as well as in research and commercial work with domestic breeds.
  • Maximise scarce resources – higher post-thaw viability rates mean you can get the most out of scarce materials.
  • Banking possibilities – endangered species can be cryopreserved for future research and breeding programmes and genetic material from valuable individual animals can now be banked, providing insurance against death, injury or disease.
  • Increasing opportunities – post-thaw sample quality can improve, with previously unviable samples reaching viable status, releasing the economic potential of otherwise inaccessible males.
© IMT International 2018